The Lions and 49ers kick off tonight at 5:15 p.m. PT (8:15 p.m. ET) on ABC, ESPN and ESPN Plus. Looking for the ManningCast?

Newsweek Sports' expert predictions for Detroit Lions vs. San Francisco 49ers on Monday Night Football Week 17.

Micah Roberts has revealed his NFL Monday Night Football bets and NFL picks against the spread for Detroit vs. San Francisco ...

SportsLine expert Jimmie Kaylor shares his Week 17 NFL DFS picks, stacks, sleepers, rankings, values, lineups and player pool ...

We're discussing Gibbs' workload, the 49ers' current situation and Detroit's newly configured defensive backfield.

Experts have released new player stat projections alongside updated prop odds for Monday's Lions-49ers NFL Week 17 Monday ...

Football game of the regular season will be between the Detroit Lions and San Francisco 49ers. Here's how to watch.

The NFL Week 17 schedule concludes with a pair of high-profile NFC teams on Monday Night Football. The Detroit Lions at San ...

Charvarius Ward will join the list of 49ers missing Monday night’s game against the Lions at Levi’s Stadium after the team ...

The Detroit Lions will lock horns with the San Francisco 49ers in Week 17 of the NFL season on Monday. This prediction is ...

Jared Goff and the Detroit Lions visit Levi’s Stadium for the final home game of this injury-riddled 49ers season ...

SportsLine expert Jimmie Kaylor shares his Week 16 NFL DFS picks, stacks, sleepers, rankings, values, lineups and player pool ...