Runes in Diablo 4 are used for creating Runewords and crafting Mythics, and these are the best ways to farm them ...

Ritual Runes gather offering, which activates the ability of the invocation rune when the required amount is reached.

Diablo 4's Vessel of Hatred is a massive gameplay improvement overall, and one of its new item types takes the game to the next level.

Runewords are back, being added to Diablo 4 in the Vessel of Hatred DLC, but how do they work and what does each Rune do?