The BRAF mutation in lung cancer means that your cancer started due to a change in the BRAF gene. It may affect your treatment options and outlook. The BRAF gene is partially responsible for cell ...

Oncology nurses and APPs play a key role in educating patients on BREAKWATER study findings and their impact on BRAF-mutant ...

It is a niche indication, given that BRAF mutations are estimated to occur in just 8% to 10% of people with metastatic colorectal cancer, but an important development for patients as these tumours ...

SAN FRANCISCO -- First-line treatment with targeted therapies plus chemotherapy offered overall response benefits in BRAF V600E-mutant metastatic colorectal cancer (mCRC), according to the ...

Oncogenic activation usually results from point mutation rather than gene rearrangement. The most common BRAF mutation is the T1796A point mutation, resulting in a glutamic acid (E) to valine (V ...

For Colorectal Cancer Awareness Month, Scott Kopetz, MD, PhD, FACP, discussed the BREAKWATER trial in metastatic BRAF ...

They found that BRAF mutations are present in a number of cancers, including approximately 50% of melanomas. They then went on to confirm mutated BRAF as an oncogene capable of driving the development ...

Colorectal cancer and pancreatic ductal adenocarcinoma that harbored the KRAS G12C mutation often carried other genetic ...

Planning Activities Are Ongoing for Next Phase of Cemsidomide Clinical Development in Multiple Myeloma and Non-Hodgkin’s Lymphoma; Trials ...